Due to the ongoing Covid-19 crisis we have scheduled next meeting in an online setting.
Gebi Team - UMR Inserm 944. CNRS 7212
Our research focuses on studying the functional role of the reorganisation of heterochromatin during early development. We use a combination of microscopy and epigenome editing technologies to investigate the contribution of the histone variant H3.3 and its chaperone Daxx in pericentromeric spatial organization of ground-state embryonic stem cells.
Laboratoire de Hématopoïèse normale et pathologique
Gustave Roussy - Inserm / Université Paris Saclay
My research focuses on the role of non-coding genome in the development of blood cancers and most particularly Acute Myeloid Leukemia. I use combination of epigenetics, genomic and screening technologies based on high throughput sequencing to interrogate enhancer dysregulation and long non-coding RNA function in leukemia.
Laboratoire "Fonctions non-conventionnelles des pores nucléaires"
Institut Jacques Monod - Équipe V. Doye
My research focuses on the role of nuclear pores in chromatin organization and gene expression during senescence.
Laboratoire Genome Instability and Stability (SInG)
Institut Cochin / Inserm
Our laboratory is interested in the subtle balances of between the different mechanisms that orchestrate DNA repair, protecting against genetic instability while allowing genetic diversity (antibodies, gametes, molecular evolution).
Chromatin dynamics in mammalian development
Institut Jacques Monod
" We strive to gain a clear understanding of the profound epigenetic consequences of DNA methylation in a window of development, which occurs in the first week of mouse embryogenesis, and the second of human, but the repercussions of which can ripple throughout life."
Laboratoire Telomeres and Repair of Chromosomes
CEA / Inserm
Dicentric chromosomes are abnormal structures that can be important contributors to pathological states. The general aim of our lab is to dissect the pathways preventing dicentrics formation and decipher how dicentric are broken upon mitotic exit and cytokinesis.
Pierre Therizols - "Daxx safeguards pericentromere integrity in embryonic stem cells"
Maxim Greenberg - "Early Embryonic Events, Life-Long Epigenetic Memory"
Past event on Jan 30
Camille Lobry - "CRISPRi screening of clustered regulatory elements reveal functional cooperating dependencies in cancer"
Charlène Boumendil - "Chromatin organization and gene expression in senescence: from the global to the fine scale"
Therese Wilhelm - “Centriole splitting and increased Microtubule Stability under Replication Stress cause Numerical Chromosomal Instability”
Stéphane Marcand - "A Telomere Protection Pathway Targeting the Rad50 Complex"
Social Time and Drinks
Institut Jacques Monod
Bâtiment Buffon, 15 rue Hélène Brion, 75205 Paris CEDEX 13 - France
L'Institut Jacques Monod (IJM), unité mixte de recherche du CNRS et de l'université Paris Diderot, est l'un des principaux pôles de recherche fondamentale en biologie de la région parisienne.
No social time this time.... social distancing and carry on.